ACE-031 (1mg)
$180.00
ACE-031 is a fusion protein consisting of the extracellular domain of activin receptor type IIB (ActRIIB) studied for its role in inhibiting myostatin and related TGF-β ligands. Research has focused on its effects on muscle mass regulation and musculoskeletal modeling.
Description
A single-component research material supplied for controlled research environments. ACE-031 (1 mg) is a recombinant fusion protein designed for research focused on activin receptor signaling pathways, muscle growth regulation, and myostatin inhibition in model systems.
Composition
• ACE-031
• Appearance: Lyophilized powder in a sealed research vial
Research Focus (non-clinical)
• Characterization of ACE-031 activity in activin receptor type IIB signaling studies
• Investigation of myostatin pathway inhibition in skeletal muscle research models
• Development of in vitro and in vivo assays for muscle mass regulation studies
• Stability and solubility profiling under controlled laboratory storage conditions
For qualified research professionals and institutional laboratories. Not for human use.
Documentation & Quality Assurance
Each lot is sourced through our verified global supply chain with emphasis on traceability and quality control.These documents are reviewed internally and displayed as they become available. Independent third-party testing is also performed on select lots to confirm identity, purity, and alignment with our internal specifications.
Important Notice
This product is intended for laboratory research use only. It is not intended for human or veterinary use, and must not be used for diagnostic, therapeutic, or clinical purposes.
This material is not a drug, medical device, or dietary supplement, and has not been evaluated by the U.S. Food and Drug Administration.
Quality & Manufacturing
All materials are sourced from carefully vetted domestic and international manufacturing partners who follow quality systems consistent with ISO and cGMP principles. Each supplier is reviewed for reliability, documentation integrity, and transparency in testing.
We require a verified purity of 99% or higher and perform independent third-party spot testing to confirm that select lots meet our internal standards for identity, purity, and composition. Where available, endotoxin testing results are included on Certificates of Analysis to verify laboratory purity; their inclusion is for research quality assessment only and does not imply suitability for human or veterinary use.
All research materials are sealed for integrity and packaged for stability during storage and transport from manufacturing through final delivery.
Molecular Specifications
CAS Number
1049557-82-5
Molecular Formula
N/A (fusion protein)
Molecular Weight
~60,000 Da (fusion protein)
Purity Standard
≥98% (SDS-PAGE)
Physical Form
Lyophilized powder
Storage
−20°C long-term; 2–8°C short-term
Appearance
White powder
Solubility
Soluble in sterile water
Amino Acid Sequence
ActRIIB extracellular domain fused to human IgG1 Fc region
Chain length: ~500 (fusion protein) amino acids
Peer-Reviewed Research
The following peer-reviewed publications represent key research on ACE-031 (1mg) conducted in laboratory and preclinical settings.
All products sold by LGI Peptides are strictly for research use only and are not intended for human consumption or therapeutic application.
[1] ACE-031 treatment of Duchenne muscular dystrophy reveals functional and structural improvements
Campbell C, et al. — Muscle & Nerve, 2017
Phase II trial demonstrating ACE-031's increase in lean muscle mass and functional improvements in DMD patients.
[2] Myostatin inhibition by ActRIIB decoy receptor increases muscle mass
Lee SJ, et al. — PNAS, 2005
Demonstrated that blocking ActRIIB signaling dramatically increases muscle mass in preclinical models.
Research Use Only: All products are intended exclusively for in-vitro laboratory research.
They are not approved for human or veterinary use, consumption, or therapeutic application.
Citations are provided for informational purposes and do not constitute medical claims.
Additional information
| Weight | 0.0625 lbs |
|---|
Certificate of Analysis
Every batch undergoes independent third-party laboratory analysis to verify identity, potency, and safety. Testing includes quantitative assay verification, heavy metals screening, and comprehensive microbial analysis.
View Certificate of AnalysisStorage Instructions
All products from LGI peptides are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.
Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.
Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.
Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.
⚠️ Important Notice:
These products are intended for research use only. Not for human consumption.
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