Tesamorelin
Price range: $150.00 through $285.00
Description
Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) studied for its ability to stimulate the pituitary gland to produce and release growth hormone (GH) in a natural, pulsatile fashion — mirroring the body's own physiological GH secretion pattern rather than introducing exogenous hormone. By working through the body's native GHRH receptor pathway, tesamorelin supports the preservation of the natural feedback loop that regulates GH levels, helping to restore youthful GH pulsatility without suppressing endogenous production.
A key downstream effect of tesamorelin-stimulated GH release is a significant increase in Insulin-like Growth Factor 1 (IGF-1). Elevated IGF-1 plays a critical role in activating hormone-sensitive lipase and promoting lipolysis — the breakdown of stored fat for energy. Research has demonstrated that this IGF-1 elevation specifically targets visceral adipose tissue (VAT), the metabolically dangerous fat stored deep within the abdominal cavity surrounding vital organs. Visceral fat is strongly associated with elevated cardiovascular risk, insulin resistance, systemic inflammation, and metabolic syndrome — making its reduction a high-priority target in metabolic health research.g., binding and cell-based workflows)
• Chromatographic method optimization for variant and impurity profiling
• Stability characterization of a lyophilized peptide under laboratory storage conditions
For qualified research professionals and institutional laboratories. Not for human use.
Documentation & Quality Assurance
Each lot is sourced through our verified global supply chain with emphasis on traceability and quality control.These documents are reviewed internally and displayed as they become available. Independent third-party testing is also performed on select lots to confirm identity, purity, and alignment with our internal specifications.
Important Notice
This product is intended for laboratory research use only. It is not intended for human or veterinary use, and must not be used for diagnostic, therapeutic, or clinical purposes.
This material is not a drug, medical device, or dietary supplement, and has not been evaluated by the U.S. Food and Drug Administration.
Quality & Manufacturing
All materials are sourced from carefully vetted domestic and international manufacturing partners who follow quality systems consistent with ISO and cGMP principles. Each supplier is reviewed for reliability, documentation integrity, and transparency in testing.
We require a verified purity of 99% or higher and perform independent third-party spot testing to confirm that select lots meet our internal standards for identity, purity, and composition. Where available, endotoxin testing results are included on Certificates of Analysis to verify laboratory purity; their inclusion is for research quality assessment only and does not imply suitability for human or veterinary use.
All research materials are sealed for integrity and packaged for stability during storage and transport from manufacturing through final delivery.
Molecular Specifications
CAS Number
218949-48-5
Molecular Formula
C₂₂₁H₃₆₆N₆₈O₆₅S
Molecular Weight
5135.77 g/mol
Physical Form
Lyophilized powder
Storage
−20°C long-term; 2–8°C short-term
Appearance
White powder
Solubility
Soluble in sterile water
Amino Acid Sequence
Trans-3-hexenoic acid-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-As…
Chain length: 44 amino acids
Peer-Reviewed Research
The following peer-reviewed publications represent key research on Tesamorelin conducted in laboratory and preclinical settings.
All products sold by LGI Peptides are strictly for research use only and are not intended for human consumption or therapeutic application.
[1] Tesamorelin reduces visceral adiposity and improves metabolic parameters in HIV-infected patients
Falutz J, et al. — New England Journal of Medicine, 2010
Phase III clinical trial demonstrating significant visceral adipose tissue reduction with Tesamorelin in HIV-associated lipodystrophy.
[2] Effects of tesamorelin on non-alcoholic fatty liver disease in HIV-infected patients
Stanley TL, et al. — Lancet HIV, 2019
Demonstrated Tesamorelin's reduction of hepatic fat fraction in HIV-associated NAFLD in a randomized controlled trial.
Research Use Only: All products are intended exclusively for in-vitro laboratory research.
They are not approved for human or veterinary use, consumption, or therapeutic application.
Citations are provided for informational purposes and do not constitute medical claims.
Additional information
| Weight | 0.0625 lbs |
|---|---|
| Dosage | 10mg, 20mg |
Certificate of Analysis
Every batch undergoes independent third-party laboratory analysis to verify identity, potency, and safety. Testing includes quantitative assay verification, heavy metals screening, and comprehensive microbial analysis.
All Available COAs
Storage Instructions
All products from LGI peptides are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.
Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.
Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.
Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.
⚠️ Important Notice:
These products are intended for research use only. Not for human consumption.
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